Acute myocardial infarction is acute coronary occlusion, interrupted blood flow, caused by the regional myocardial ischemic necrosis.
Pathogenesis
Coronary atherosclerosis causing lumen cardiac insufficiency and narrow, and the collateral circulation has not yet been established, due to the following reasons to increase myocardial ischemia in myocardial infarction.
First, completely occluded coronary vascular disease, atherosclerosis or endometrial hemorrhage, or lumen, arterial thrombosis persistent cramps, so that the lumen in complete occlusion.
Second, cardiac output dropped in shock, dehydration, bleeding, serious arrhythmia caused by surgery or cardiac output dropped, coronary flow serious shortage of irrigation.
Third, cardiac output increase aerobic take severe physical, emotional or drama or blood pressure, left ventricular load surge, increased secretion of catecholamine, aerobic cardiac output to be increased.
AMI often occurred in meal (especially the large consumption of fat), quiet sleep, or force the stool, this postprandial lipid due to increased blood viscosity is high, platelet adhesion enhancements, local blood flow slow, easy-platelet Gathered that thrombosis; sleep, the higher vagal tone, easily cause coronary artery spasm, increase the heart load forced the stool, these factors are conducive to the occurrence of acute myocardial infarction.
AMI can also occur in non-coronary atherosclerosis in coronary artery spasm, sometimes due to coronary thrombosis, inflammation, caused by congenital malformation. Myocardial infarction after a serious arrhythmia, shock or heart failure, coronary artery that may further reduce the flow of irrigation, expand the scope of myocardial necrosis.
5/13/2008
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