5/01/2008

Asthma-related clinical examination.

First, blood routine examination

Attack may have increased eosinophils. As with infection have increased the total number of leukocytes, classification higher proportion of neutrophils. The inspections

Second, sputum examination

Smear visible under the microscope more eosinophils, a sharp edge crystallization (Charcort-Leyden crystal), mucus suppository (Curschmann spring) and transparent asthma-(Laennec beads). If the merger respiratory bacterial infection, the sputum smear Gram stain, bacterial culture and drug sensitivity tests to pathogen diagnosis and treatment.

Third, respiratory function tests

In an asthma attack when the flow of the breath of all the indicators were significantly decreased, forced expiratory volume in one second (FEV1), forced expiratory accounts for one second forced vital capacity ratio (FEV1/FVC%), the largest medium-term flow of breath (MMFR) , 25% and 50% of vital capacity, the largest expiratory flow (MEF25% and MEF50%) and peak expiratory flow rate (PEFR) are reduced. Remission can be recovered. Effective Bronchodilation of these indicators will improve. Have reduced lung capacity, the residual gas volume increase, functional residual capacity and increase the total lung, residual gas higher percentage of the total lung.

4, blood gas analysis

If an asthma attack at the lack of oxygen, may have PaO2 lower, due to excessive ventilation PaCO2 will decline, pH value increased, showing respiratory alkalosis. Such as severe asthma, airway obstruction increase will enable the CO2 retention, PaCO2 increased performance respiratory acidosis. Such as hypoxia obviously, can be combined metabolic acidosis.

5, chest X-ray examination

Early in the asthma attack that Liangfei through increased brightness, was over-inflated state in remission have no obvious abnormalities. Such as with respiratory infections, and the increase in the foreseeable Fei Wenli inflammatory infiltration shadow. At the same time attention should be paid to atelectasis, or pneumothorax mediastinal emphysema and other complications exist.

6, the specific allergens complement test

Available allergens absorption of radioactive test (RAST) of specific lgE, allergic asthma patients with lgE be 2-6 times higher than normal. In remission inspection can determine if the allergens, but should prevent allergic reactions.ĺ—śtablets or alkaline cells to release histamine test calculation of histamine release rate,> 15% positive. Determination of blood and also in the respiratory secretion lgE, lgA, lgM, such as immunoglobulin.

7, skin sensitivity test

In asthma remission with the original suspicious skin allergies or scratches in the skin test, qualified for inhalation provocation test, to make a diagnosis of allergens. It should be noted highly sensitive patients can sometimes be induced asthma and systemic reactions, and even anaphylactic shock. Should be closely observed, corresponding to take timely treatment.

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