Diabetes risk of atherosclerosis
People with diabetes easy arteriosclerosis around the body, including brain, heart, kidney, peripheral vascular, in the main obstacle lies in fat metabolism, followed by hypertension.
In diabetes, in the abnormal fat metabolism, in insulin secretion by extremely low body fat and the majority of patients. The lack of insulin secretion in extreme circumstances, the decomposition of lipase activity will increase, resulting in a large number of free fatty acids out. Thus, in such circumstances, free fatty acids in the blood of about 1 / 3 poured into the liver, the synthesis of three acid fats (commonly known as the neutral fat), 3 acid synthesis for further oil very low density lipoprotein. However, the size of obesity patients, although a higher concentration of insulin, insulin but the body of the organization a considerable role in the resistance of the insulin can not bring into full play the role of circumstances, free fatty acids also increased, with the lower insulin secretion Shututonggui the situation. 3 acid grease and very low density lipoprotein synthesis will be increased, this is the general diabetes abnormal fat metabolism characteristics.
A small number of patients who may also be combined cholesterol increased, while harmful to the human body fat increased, on the other hand the human body beneficial high-density lipoprotein concentration instead of declining. This high-density lipoprotein in the body can be distributed in vascular smooth muscle of the free surface to attract lipoprotein cholesterol molecules inside, repeatedly attracted, with free cholesterol to the liver, through the alienation of bile acids, cholesterol from these in vitro. So high-density lipoprotein in the blood vessels in the human body, like scavenger of the work to prevent the progress of atherosclerosis.
In addition, the diabetes rate of hypertension is higher than most people, this is also easy to promote the cause of atherosclerosis. Hypertension and arteriosclerosis mutual influence between them, easy to promote atherosclerosis hypertension, atherosclerosis and high blood pressure is also easy to make, diabetes hypertension show people more easily, whether from vascular sclerosis, or the status of a single, easy to speed up the hardening of blood vessels to .
5/04/2008
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