The stubborn and serious hyperlipidemia, can be given appropriate medical treatment, has yet to be very physical requirements of the lipid-lowering drugs. Most of lipid-lowering effect only short-term and long-term use is apparent side effects. Therefore, drug therapy should be considered as high risk for coronary heart disease, lipid metabolism disorder measure of last resort, and with non-drug therapy to be conducted jointly.
Hyperlipidemia strict diet control after three to six months later, the lipid levels are still significantly higher, especially for the elderly and other risk factors (such as diabetes, hypertension and family history of cardiovascular disease, etc.) There must be given to drugs Treatment. Drug treatment should still adhere to diet therapy. Hypolipidemic drugs currently used are as follows several categories. Drug treatment must be under the guidance of doctors, after comprehensive analysis of history choose to use.
1, phenoxy-acids: such drugs fenofibrate, gemfibrozil, bezafibrate, and so on. Phenoxy-acid drugs hypolipidemic effect strong, fast onset of action, down the role of triglyceride than cholesterol-lowering effect of the strong.
2, 3 hydroxymethyl-3酰- coenzyme A reductase inhibitors: such drugs lovastatin Ding, Simvastatin, pravastatin, and so on. Such drugs down the main cholesterol, lipid-lowering effect strong, fast onset of action.
3, nicotinic acid categories: oxygen of such drugs in a more commonly used glipizide, lower than the role of serum triglyceride-lowering cholesterol.
4, polyunsaturated fatty acids categories: all kinds of plant seeds, including oil. Such as rubber seed oil, evening primrose son, silymarin seed oil and fish preparations. These drugs have hypolipidemic and lower blood viscosity, but more moderate role.
5, the Pan-sulfur triethylamine: coenzyme A derivatives, have lower serum cholesterol and triglyceride and increased high-density lipoprotein - the role of cholesterol.
6, PSS (PPS): seaweed is summarized as raw materials of the type of marine drug heparin. Engage in a blood-low blood viscosity, expansion of blood vessels and lower blood fat, increase the role of HDL levels. Mainly used for ischemic cardiovascular disease prevention.
7, other hypolipidemic drugs: categories such as Ginkgo biloba (Taponin) experimental serum that can triglyceride (TG) decreased significantly.
5/11/2008
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