How diagnosis of Legionella pneumonia?

How diagnosis of Legionella pneumonia

Legionella bacteria have identified four diagnostic tests: culture, exudation of direct fluorescent antibody staining, using indirect fluorescent antibody serum for examination and analysis of urine antigen. Jieju four specific, but not particularly sensitive.

Pathogens from the sputum, tracheal suction, material, or bronchial aspiration of brushing, lung biopsy, pleural liquid or found in the blood. Legionella bacteria are not normal flora, the diagnostic value of a positive culture, but confirmed that the use of other technologies Case, sputum culture positive rate of only 30% to 70%. Cultivate and direct immune staining require high technology. Urine antigen analysis is relatively easy to do gymnastics and the start of treatment in a longer period of time may have found positive, but This method can only detect the serotype 1 of Legionella pneumophila (accounting for 70 percent of all cases). Titer can prove that increased four times (at least ≥ 1:128), serological diagnosis can be made. A rehabilitation period of serum Can display titer ≥ 1:256, coupled with the corresponding clinical symptoms can be effectively supported the diagnosis. When the need to make treatment decisions, a diagnosis of the titer increased general does not appear, and the incidence is usually three to six weeks after the It appears.