Vitamin C, E to prevent arteriosclerosis effects vary from person to person

Vitamin C, E to prevent arteriosclerosis effects vary from person to person

According to overseas media reports, the United States and Canada, a joint research team at the just-published in the April 2004 period, "Diabetes Care" published research papers that the antioxidant vitamin C and vitamin E effects vary from person to person, can be "effective, "And" invalid "two. The "effective", the vitamin does have the effect of preventing atherosclerosis, but "invalid" there is no preventive effect, and sometimes it will lead to atherosclerosis symptoms worsen.
Began to deteriorate after the symptoms of atherosclerosis, vascular thinning hardens, the solidification triggered embolization blocks blood, heart disease and stroke lead to high risk.
Lead to the deterioration of atherosclerosis is caused by reactive oxygen species, such as oxidative stress (Stress). Malignant cholesterol (LDL cholesterol) oxidation, attached to the artery wall, causing blood vessels thinner, blood coagulation - This is a process of atherosclerosis.
Prior to the animal experiments have confirmed that a strong anti-oxidation of vitamin C and E can inhibit the oxidation of LDL cholesterol and prevent arteriosclerosis. But in man-made object to the clinical trials were carried out "effective" and "invalid" and "counterproductive" research. The study, vitamin C and E are valid vary from person to person, depending on red blood cells in the human body for the cycle, "with beads of" type of protein gene. With globin gene has type 1 and type 2 in two forms, each with globin gene has two genes from the father and the mother of a successor, the combination of three phenotype: 1-2 gene (1 / 1 Type), 2-2 gene (2 / 2), a type 1 gene and a type 2 gene (1 / 2).
The report said, 1 / 1 person (with two 1-of-globin gene) intake of antioxidant vitamins can prevent arteriosclerosis, and antioxidant vitamins to 1 / 2 (one each type 1 and type 2 with beads Gene) and 2 / 2 (with two 2-globin gene combination) did not effect the prevention, in particular, 2 / type 2 diabetes and the people, taking antioxidant vitamins it will speed up atherosclerosis. - Protein combination is the role of "red blood cells of the circulatory system", that is the end of life recycling of red blood cells, once again transported to the liver using the iron grade.
Has confirmed antioxidant vitamins does not work, with a combined 2-of-globin gene, the efficiency of lower circulation, the concentration of iron in the blood very high, and this iron in the blood may be the "bad elements." Taking vitamin C and other antioxidant vitamins, iron (iron oxide, Fe3 +) be reverted, in the form of ferrous oxide (Fe2 +), and ferrous oxidation of LDL cholesterol particularly the ability, that is, by its own 2 - Globin gene with the iron in the blood, thus taking antioxidant vitamins after a large number of ferrous oxide, it has accelerated atherosclerosis. However, this conclusion is based on the trial of 300 people drawn by the data, credibility is not high. Europe and the United States is the largest so far launched "HOPE", "HPS" tens of thousands of people, such as the large-scale testing, the effect of antioxidant vitamins for investigation.
Study group, should use these large-scale test data, according to different types of globin gene that results of genetic types that really affect the effectiveness of antioxidant vitamins.