5/11/2008

What kind of patients it is not appropriate to cholesterol-lowering treatment?

First of all, active hepatitis patients should not use cholesterol-lowering drugs. Such lipid-lowering drugs in the liver metabolism, thus increasing the liver damage.

Second, pregnant or lactating women should not use cholesterol-lowering drugs. Because the atherosclerosis process is chronic, disabling lipid-lowering drugs during pregnancy on the treatment of primary hypercholesterolemia little impact in the long-term results; Moreover, the biological synthesis of cholesterol and other products is a necessary component of fetal development , Including steroids and cell membrane synthesis. He set type lipid-lowering drugs in lowering cholesterol biosynthesis, but also reduce the cholesterol biosynthesis pathway of other products. Therefore, pregnant women taking such drugs may be detrimental to the hypolipidemic fetus.

Hypolipidemic drugs and their metabolites are secreted by human milk is still a lack of research. Because many drugs as human milk secretion, but also because of the potential side effects of lipid-lowering drugs, breast-feeding women should not be taking lipid-lowering drugs.

Finally, it must be stressed that not all patients with coronary heart disease are suitable for cholesterol-lowering treatment, senior citizens over the age of 70 elderly patients with chronic congestive heart failure, dementia, cerebral vascular disease or advanced activities of patients with malignant tumors, it is not appropriate Taking lipid-lowering therapy.

No comments: